Detection of circulating type 3 vaccine-derived polioviruses in French Guiana, May to August 2024

Stéphanie Raffestin (1, 2) , Ambre Tinard (3, 4, 5) , Antoine Enfissi (2, 6) , Marie-Line Joffret (3, 4, 5) , Timothée Lichtenstein (6) , Sourakhata Tirera (7) , Laura Zanetti (8) , Marie Barrau (9) , Francky Mubenga (10) , Adrien Ortelli (10) , Christophe N Peyrefitte (2, 11) , Anne Lavergne (7) , Dominique Rousset (2, 6) , Maël Bessaud (3, 4, 5)

1 LHE - Laboratoire Hygiène et Environnement [Institut Pasteur de la Guyane]
2 GIS OBEPINE - OBEPINE OBservatoire ÉPIdémiologique daNs les Eaux usées - Wastewater-based Epidemiology [Paris, France]
3 Signalisation antivirale - Virus sensing and signaling
4 CNR - laboratoire associé - Centre National de Référence Entérovirus et Parechovirus [Paris]
5 CC-OMS / WHO-CC - Centre collaborateur de l'OMS - Recherche sur l’épidémiologie et la macro-évolution des poliovirus et des entérovirus non-polio - WHO Collaboration Centre Epidemiology & macro-evolution of polioviruses and non-polio enteroviruses
6 Laboratoire de virologie [Cayenne, Guyane française]
7 Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française]
8 Direction des maladies infectieuses - Infectious Diseases Division [Saint-Maurice]
9 Santé publique France Guyane
10 ARS Guyane - Agence Régionale de Santé Guyane
11 Institut Pasteur de la Guyane

Circulating type 3 vaccine-derived polioviruses (cVDPV3s) were detected in three wastewater samples collected in French Guiana from May through August 2024. As the oral polio vaccine is not used in French Guiana, this event involved an import either of cVDPV3s themselves or of a vaccine strain from which the cVDPV3s emerged in French Guiana. This highlights the importance of environmental surveillance for the detection of silent poliovirus circulation. Eliminating any pockets of cVDPVs is crucial for the polio eradication programme.

Domaines: Virologie

Stéphanie Raffestin, Ambre Tinard, Antoine Enfissi, Marie-Line Joffret, Timothée Lichtenstein, et al.. Detection of circulating type 3 vaccine-derived polioviruses in French Guiana, May to August 2024. Eurosurveillance, 2024, 29 (5), pp.2400705. ⟨10.2807/1560-7917.ES.2024.29.45.2400705⟩. ⟨hal-04772605⟩