Enniatins and Beauvericin Emerging Mycotoxins Affect Pigs' Metabolome - Biosynthèse & Toxicité des Mycotoxines Access content directly
Conference Poster Year : 2023

Enniatins and Beauvericin Emerging Mycotoxins Affect Pigs' Metabolome

Emilien Jamin
Jean-François Martin
  • Function : Author
  • PersonId : 1140388
Barbara Novak
  • Function : Author
  • PersonId : 1139971
Dian Schatzmayr
  • Function : Author
  • PersonId : 1120979
Olivier Puel
Philippe Pinton

Abstract

In addition to deoxynivalenol, fumonisins and zearalenone, Fusarium fungi produce other toxins such as beauvericin or enniatins, which are called “emerging” mycotoxins (EMs). Occurrence data and biological effects for EMs are still limited. Recently, feed ingredients were shown to contain 66% to 98% of beauvericin, enniatin B, aurofusarin or apicidin [1]. In vitro, data suggest that BEA and ENN induce cytotoxicity, oxidative stress and apoptosis. In vivo, while they do not induce apparent acute mycotoxicosis, no conclusion can be drawn on chronic exposure. To study the impact of EMs, we conducted a LC-MS based metabolomics study of plasma and liver of piglets (5 weeks) fed with a mixture of enniatins B, B1 and beauvericin during 14 days.
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Dates and versions

hal-04357544 , version 1 (21-12-2023)

Identifiers

  • HAL Id : hal-04357544 , version 1

Cite

Emilien Jamin, Justin Oules, Jean-François Martin, Barbara Novak, Dian Schatzmayr, et al.. Enniatins and Beauvericin Emerging Mycotoxins Affect Pigs' Metabolome. ASMS conference, Jun 2023, Houston (TX), United States. ⟨hal-04357544⟩
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